RA Capital led the companys $336 million Series C ahead of the companys August IPO, though the firm hadnt participated in the companys earlier funding rounds. Texas Halo Fund is an investment firm based in Houston, Texas. Leading a funding round is a big undertaking. It is typical for venture capital firms to identify and back companies in high technology industries and so venture capital is most active in the fast-growing technology and life sciences or biotechnology fields. New Leaf Venture Partners (NLVP) invested in Biopharmaceuticals during its growth and venture phases. Abogen Biosciences Co., Ltd. Headquarters: Suzhou Abogen Biosciences makes it on this list by virtue of an impressive $700 million Series C round that it bagged in August 2021 one of the biggest-ever private biotech funding rounds. Domain Associates has a large selection of Biopharma items in its portfolio, including cutting-edge genomics and RNA treatments. More than 90 companies have gone public, up from 81 in 2020 and 49 in 2019, according to SVB Leerink analysts. Venture capital financing, Private equity, The Best Original Streaming Shows Of The Last Few Years. They have made over 177 investments in HealthTech, Biotechnology and HealthTech companies. Fierce Life Sciences Events. The Indian startup/ VC ecosystem will truly come of age It has even created startups in-house over the past couple of years. Does the firm have any background in technology similar to yours? The firm prefers to invest in the aerospace, defense, energy, healthcare, information technology, industrials, and manufacturing sectors in Texas. California-based Interwest Partners focuses on healthcare and IT. Additionally, Bain Capital Crypto closed a $500 million fund in Massachusetts biopharma firms raised a record $13.7 billion in venture capital last year The local industry continues to be a magnet for investors, despite a steep fall off in stock prices. The company is steadily growing its life science footprint, emphasizing infrastructure, financial instruments, and real estate. US biotechs still led on investments, although Europe The firm also has a biotech-specific team called DCVC Bio that's raising a $350 million fund for later-stage investments. The firm is headquartered in San Francisco, California. Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! Third-ranked Flagship Pioneering, for instance, was driven by just two IPOs in 2021. WebMarket-leading rankings and editorial commentary - see the top law firms & lawyers for Venture capital and emerging companies in United States. In addition to its private-equity investing, RA Capital has brought companies public through SPACs with mixed results. Reporting by Sohini Podder and Noor Zainab Hussain in Bengaluru; Editing by Maju Samuel. Copyright 2023 Genetic Engineering & Biotechnology News. The firm seeks to invest in seed-stage, early-stage, and later-stage companies. Largest investment: 7.9 million shares of Vor Biopharma worth $142 million at the time of its IPO, Total holding value of 2021 IPOs: $1.3 billion. Boston Cambridge Massachusetts Consistently, the top state for biotechnology industries in Massachusetts, particularly in the Greater Boston area. Alex Philippidis Senior News Editor Genetic Engineering & Biotechnology News. The management team, combined with its advisory board, includes seasoned entrepreneurial, medical device sector, venture capital, regulatory, and scientific expertise. The largest deal of 2021 was the transaction of Treeline Biosciences (USD 735m), while the most active investor was Alexandria Venture Investments with 51 investments in 2021. The firm prefers to invest in the direct-to-consumer, food and beverage, health and beauty, sports and fitness, apparel and accessories, accessible luxury, wellness, LOHAS, aging population, sustainable products, demand for personalization, humanization of pets, omnichannel, fem tech, and end of life sectors. Largest investment: 26.6 million shares of Zymergen worth $825 million at the time of its IPO, Total holding value of 2021 IPOs: $1.1 billion. Eighteen firms held shares worth $400 million or more in biotech companies that went public this year. To date, over 70 of the companys life science products have received FDA approval. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Fund size and status: More than $3 billion in committed capital across nine funds. Largest investment: 44 million shares of Sana Biotechnology worth $1.1 billion at the time of its IPO, Total holding value of 2021 IPOs: $1.9 billion. Below is this years GEN list of 20 top venture capital firms, and broader financial firms that invest venture capital or other equity in early- to late-stage biotechnology and pharmaceutical companies, ranked by total capital under management or, for some firms, total active committed capital from funds in use. Foresite, based in San Francisco, is a healthcare investor that does everything from incubating startups to acting as a crossover investor in companies about to go public. The firm seeks to make investments in companies operating in business software, consumer internet, cloud service, enterprise software and other technology sectors. Medtech. Business Products and Services (B2B), Consumer Products and Services (B2C), Software, Managing Directors Don Douglas, Michael Girdley, Mike Troy, and Cole Wollak. All quotes delayed a minimum of 15 minutes. Largest investment: 13.2 million shares of Lyell Immunopharma worth $225.8 million at the time of its IPO, Total holding value of 2021 IPOs: $400.2 million. Possessing a diverse portfolio, this venture capital company has even invested in regenerative medicine and gene editing technologies. Just eight months into this new SPAC phenomenon, weve already seen signs of oversaturation in the market, with a recent uptick in the number of downsized SPAC IPOs, PitchBook analysts said. Founded in 2005, GOOSE Capital is a venture capital firm based in Houston, Texas. Synthetic biology investment set a nearly $8 billion record The New York-based OrbiMed Healthcare Fund Management has made various investments in the life sciences sector, including MedTech and Biopharma. That seventh fund closed $50 million higher than the $400 million offering amount that the firm stated back on June 17, when it disclosed its plan to raise the fund in a Form D filing with the U.S. Securities and Exchange Commission. Asia Pacific ; Year established: Established 1993 as Schroder Ventures Life Sciences. WebThe lifeblood of revolutionary medical technologies is venture funding. Largest investment: 11.9 million shares of Century Therapeutics worth $238.5 million at the time of its IPO, Total holding value of 2021 IPOs: $416.6 million. CipherBio data reveals that the US is an undisputed leader in life science space as the location attracting most of the Biotech funding since the beginning of 2019 69% of all deals closed in the top 10 locations globally accounts for the US (Figure 2). Accel is a venture capital firm that concentrates on the following technology sectors: Consumer, Infrastructure, Media, Mobile, SaaS, Security, Customer care services, Enterprise software, and E-commerce. These were the top 10 VC deals in Mass. Insights about top trending companies, startups, investments and M&A activities, notable investors of these companies, their management team, and recent The company focuses on first-in-class goods and cutting-edge, disruptive technologies. biotech in 2021 VIEW SLIDESHOW 10 photos By Rowan Walrath Life Sciences Reporter, Boston Business Journal Dec 29, Amidst rising interest rates and the looming threat of recession, the once-hot IPO market has come to a grinding halt. Who has the most invested in funding up-and-coming biotechs? The firm seeks to invest in B2B SaaS companies. 9 See announcement on the firms blog, http://indexventures.com/news-room/blog/our-new-fund-for-building-iconic-businesses Founded in 2005, Mercury Fund is a venture capital firm based in Houston, Texas. It is a part of the more prominent Novo Holding company, whose investments are more varied. WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! Following is a list of the top 15 venture capital firms in 2023. The Legal 500; Europe, Middle East & Africa . Blackstone, one of the largest private venture capital firms, founded Blackstone Life Sciences in 2018 after acquiring Clarus Ventures, an equity firm with $2.6 billion in assets. The capital total is a staggering 46% increase from its last set of funds, closed in May 2021 at $1.3 billion. Although the two firms emerged as leaders in the data, they still make up a small part of the more than $120 billion in venture capital funds globally that poured into health and biotech startups as of Dec. 1 this year, Crunchbase data shows. There is mixed news heading into 2021 on the COVID-19 pandemic front, with rising infection levels and a handful of vaccines showing promise. Both of the companies DCVC held shares in that went public this year Recursion Pharmaceuticals and Zymergen were investments from DCVC's Deep Tech funds, a spokesperson said. 11 On Nov. 14, the firm submitted a Form D filing stating that partners were raising funds toward a ninth fund, to be named Bessemer Venture Partners IX Institutional. PitchBook said more companies, especially large-sized technology startups, are expected to take the direct listing route to go public instead of an IPO in 2021. Morgenthaler VenturesLife Sciences Team, City (cities) where offices are located: Palo Alto, CA; Boston; Boulder, CO, Fund size and status: More than $2.5 billion under management, Current fund: $400 million Fund IX, closed 2008 and used in part for investment in life-sciences companies. Insights about top trending companies, startups, investments and M&A activities, notable investors of these companies, their management team, and recent It closed its second Xontogeny-focused fund in May, giving it another $515 million to invest in a dozen or more companies. The Baltimore-based company was active in a handful of 2021 biotech IPOs, including Evotec, Longboard Pharmaceuticals, and Imago BioSciences. It is typical for venture capital firms to identify and back companies in WebCaroline Lembck is a distinguished executive in the biotechnology and finance industries, recognized for her remarkable achievements. Largest investment: 53.8 million shares of LianBio worth $861 million at the time of its IPO, Total holding value of 2021 IPOs: $1.2 billion. Largest investment: 12.1 million shares of Instil Bio worth $244 million at the time of its IPO, Total holding value of 2021 IPOs: $425.7 million. The firms themselves are the sources of much of the information, though in some instances, amounts of capital under management were calculated by adding the value of newly closed funds with previously disclosed amounts. Blume Ventures Blume Ventures is an early-stage and seed-stage venture fund that has its headquarters in Mumbai, Maharashtra, India. Healthtech and biotech has consistently been a top sector for the destination of venture capital in recent years. Latest biotech merger sees aimless Adamis snapped up by DMK - FierceBiotech 4h ago On the other hand, the number of special purpose acquisition companies (SPACs), which raise funds through an initial public offering (IPO) to acquire another company within two years, is expected to dwindle in 2021 compared to 2020, PitchBook said. 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